It will depend on your draw lenght and the weight of your point for bow weights.
The 500 spine a 30 to 45 lb bow
The 400 spine a 45 to 58 lb bow
The 300 spine a 58 lb plus.
You may have to experiment with your point weight or cut the arrow and reinstall the inserts to obtain the correct spine for accurate arrow placement.
Answered on 12/3/2013 by Keith from 3Rivers Archery